Fosdenopterin

CHEMBL2338675 Phase 4 Disetujui Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

363.2 g/mol

LogP

-4.0

Phase

4

This medication is used to treat molybdenum cofactor deficiency type A, an extremely rare and severe genetic disorder that affects the brain due to the buildup of toxic sulfite. It works as a replacement for cyclic pyranopterin monophosphate (cPMP), a precursor that the body cannot produce on its own. Treatment must begin very early in life to prevent irreversible neurological damage.

Berat Molekul

363,2200 g/mol

LogP

-4,00

TPSA

197,00 Å²

Lipinski RO5

Gagal

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Struktur 2D

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SMILES

Nc1nc(=O)c2c([nH]1)N[C@@H]1O[C@@H]3COP(=O)(O)O[C@@H]3C(O)(O)[C@@H]1N2

InChI

InChI=1S/C10H14N5O8P/c11-9-14-6-3(7(16)15-9)12-4-8(13-6)22-2-1-21-24(19,20)23-5(2)10(4,17)18/h2,4-5,8,12,17-18H,1H2,(H,19,20)(H4,11,13,14,15,16)/t2-,4-,5+,8-/m1/s1

Molecular Formula

C10H14N5O8P

HBD / HBA

7 / 11

Ikatan yang Dapat Dirotasi

0

Atom Berat

24

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Pertanyaan yang Sering Diajukan

This medication is used to treat molybdenum cofactor deficiency type A, an extremely rare and severe genetic disorder that affects the brain due to the buildup of toxic sulfite. It works as a replacement for cyclic pyranopterin monophosphate (cPMP), a precursor that the body cannot produce on its own. Treatment must begin very early in life to prevent irreversible neurological damage.

Yes, Fosdenopterin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2338675. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 135463437. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Struktur

Data Cepat

Rumus: C10H14N5O8P
Sinonim: 1

Tautan Eksternal

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Penyangkalan Medis

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.