Histamine
This naturally occurring chemical messenger plays a central role in immune responses, allergic reactions, gastric acid secretion, and neurotransmission. As a therapeutic agent, histamine has been used in immunotherapy protocols and studied in combination treatments for melanoma and leukemia. Paradoxically, administering histamine can in some contexts modulate immune function beneficially.
Berat Molekul
111,1500 g/mol
LogP
-0,70
TPSA
54,70 Ų
Lipinski RO5
Lulus
Area Terapeutik
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Struktur 2D
Cite this structure
Embed this structure
SMILES
NCCc1c[nH]cn1
InChI
InChI=1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)
Molecular Formula
C5H9N3
HBD / HBA
2 / 2
Ikatan yang Dapat Dirotasi
2
Atom Berat
8
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Pertanyaan yang Sering Diajukan
This naturally occurring chemical messenger plays a central role in immune responses, allergic reactions, gastric acid secretion, and neurotransmission. As a therapeutic agent, histamine has been used in immunotherapy protocols and studied in combination treatments for melanoma and leukemia. Paradoxically, administering histamine can in some contexts modulate immune function beneficially.
Yes, Histamine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL90. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 774. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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