Hydrocortisone Cypionate

CHEMBL1549 Phase 4 Disetujui Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

486.6 g/mol

LogP

4.7

Phase

4

A cypionate ester of hydrocortisone that provides an extended-release profile when administered orally, used as a replacement therapy in adrenocortical insufficiency. The long-chain ester slows metabolism and extends the duration of glucocorticoid activity. This formulation was designed to mimic the natural diurnal pattern of cortisol secretion.

Berat Molekul

486,6000 g/mol

LogP

4,70

TPSA

101,00 Å²

Lipinski RO5

Lulus

Area Terapeutik

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Benign Prostatic Hyperplasia Glaucoma Pain Management Non-Small Cell Lung Cancer Rheumatoid Arthritis Asthma Chronic Obstructive Pulmonary Disease Parkinson's Disease Generalized Anxiety Disorder Insomnia Melanoma Inflammatory Bowel Disease Psoriasis Systemic Lupus Erythematosus Multiple Sclerosis Stroke Obesity Lymphoma Type 2 Diabetes Hypertension Major Depressive Disorder Breast Cancer Atopic Dermatitis Gout Chronic Pain HIV/AIDS Tuberculosis Heart Failure Atrial Fibrillation Prostate Cancer Colorectal Cancer Leukemia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Struktur 2D

SVG PNG

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SMILES

C[C@]12CCC(=O)C=C1CC[C@@H]1[C@@H]2[C@@H](O)C[C@@]2(C)[C@H]1CC[C@]2(O)C(=O)COC(=O)CCC1CCCC1

InChI

InChI=1S/C29H42O6/c1-27-13-11-20(30)15-19(27)8-9-21-22-12-14-29(34,28(22,2)16-23(31)26(21)27)24(32)17-35-25(33)10-7-18-5-3-4-6-18/h15,18,21-23,26,31,34H,3-14,16-17H2,1-2H3/t21-,22-,23-,26+,27-,28-,29-/m0/s1

Molecular Formula

C29H42O6

HBD / HBA

2 / 6

Ikatan yang Dapat Dirotasi

7

Atom Berat

35

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Pertanyaan yang Sering Diajukan

A cypionate ester of hydrocortisone that provides an extended-release profile when administered orally, used as a replacement therapy in adrenocortical insufficiency. The long-chain ester slows metabolism and extends the duration of glucocorticoid activity. This formulation was designed to mimic the natural diurnal pattern of cortisol secretion.

Yes, Hydrocortisone Cypionate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1549. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 223253. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Struktur

Data Cepat

Rumus: C29H42O6

Tautan Eksternal

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Penyangkalan Medis

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.