Hydroxyzine Pamoate
This pamoate salt form of hydroxyzine is used in capsule form for anxiety and tension relief, as well as allergic conditions. The pamoate salt allows for a slightly different absorption profile compared to the hydrochloride salt. Like other hydroxyzine formulations, it carries anticholinergic side effects including dry mouth and drowsiness.
Berat Molekul
763,3000 g/mol
TPSA
151,00 Ų
Area Terapeutik
Mekanisme Kerja
Competitively blocks muscarinic acetylcholine receptors, reducing parasympathetic nervous system activity. Effects include decreased secretions, bronchodilation, and relaxation of smooth muscle.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Competitively blocks muscarinic acetylcholine receptors, reducing parasympathetic nervous system activity. Effects include decreased secretions, bronchodilation, and relaxation of smooth muscle.
Struktur 2D
Cite this structure
Embed this structure
SMILES
O=C(O)c1cc2ccccc2c(Cc2c(O)c(C(=O)O)cc3ccccc23)c1O.OCCOCCN1CCN(C(c2ccccc2)c2ccc(Cl)cc2)CC1
InChI
InChI=1S/C23H16O6.C21H27ClN2O2/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29;22-20-8-6-19(7-9-20)21(18-4-2-1-3-5-18)24-12-10-23(11-13-24)14-16-26-17-15-25/h1-10,24-25H,11H2,(H,26,27)(H,28,29);1-9,21,25H,10-17H2
Molecular Formula
C44H43ClN2O8
HBD / HBA
5 / 10
Ikatan yang Dapat Dirotasi
12
Atom Berat
55
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Pertanyaan yang Sering Diajukan
This pamoate salt form of hydroxyzine is used in capsule form for anxiety and tension relief, as well as allergic conditions. The pamoate salt allows for a slightly different absorption profile compared to the hydrochloride salt. Like other hydroxyzine formulations, it carries anticholinergic side effects including dry mouth and drowsiness.
Competitively blocks muscarinic acetylcholine receptors, reducing parasympathetic nervous system activity. Effects include decreased secretions, bronchodilation, and relaxation of smooth muscle.
Yes, Hydroxyzine Pamoate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200467. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 25096. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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