Ioxaglic Acid
This iodinated contrast agent is a low-osmolality ionic compound (ionic dimer) used for intravascular procedures including coronary angiography and venography. Its lower osmolality compared to older ionic monomeric agents reduces cardiovascular stress and patient discomfort. It was among the first low-osmolality contrast agents developed.
Berat Molekul
1268,9000 g/mol
LogP
2,80
TPSA
194,00 Ų
Lipinski RO5
Gagal
Mekanisme Kerja
Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.
Struktur 2D
Cite this structure
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SMILES
CNC(=O)c1c(I)c(C(=O)NCC(=O)Nc2c(I)c(C(=O)O)c(I)c(C(=O)NCCO)c2I)c(I)c(N(C)C(C)=O)c1I
InChI
InChI=1S/C24H21I6N5O8/c1-7(37)35(3)20-17(29)10(21(39)31-2)13(25)11(18(20)30)23(41)33-6-8(38)34-19-15(27)9(22(40)32-4-5-36)14(26)12(16(19)28)24(42)43/h36H,4-6H2,1-3H3,(H,31,39)(H,32,40)(H,33,41)(H,34,38)(H,42,43)
Molecular Formula
C24H21I6N5O8
HBD / HBA
6 / 8
Ikatan yang Dapat Dirotasi
10
Atom Berat
43
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Pertanyaan yang Sering Diajukan
This iodinated contrast agent is a low-osmolality ionic compound (ionic dimer) used for intravascular procedures including coronary angiography and venography. Its lower osmolality compared to older ionic monomeric agents reduces cardiovascular stress and patient discomfort. It was among the first low-osmolality contrast agents developed.
Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.
Yes, Ioxaglic Acid is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201291. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 3742. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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