Lefamulin
This pleuromutilin antibiotic treats community-acquired bacterial pneumonia with activity against multidrug-resistant pathogens.
Berat Molekul
507,7000 g/mol
LogP
4,30
TPSA
135,00 Ų
Lipinski RO5
Lulus
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Struktur 2D
Cite this structure
Embed this structure
SMILES
C=C[C@]1(C)C[C@@H](OC(=O)CS[C@@H]2CC[C@@H](N)C[C@H]2O)[C@]2(C)[C@H](C)CC[C@]3(CCC(=O)[C@H]32)[C@@H](C)[C@@H]1O
InChI
InChI=1S/C28H45NO5S/c1-6-26(4)14-22(34-23(32)15-35-21-8-7-18(29)13-20(21)31)27(5)16(2)9-11-28(17(3)25(26)33)12-10-19(30)24(27)28/h6,16-18,20-22,24-25,31,33H,1,7-15,29H2,2-5H3/t16-,17+,18-,20-,21-,22-,24+,25+,26-,27+,28+/m1/s1
Molecular Formula
C28H45NO5S
HBD / HBA
3 / 7
Ikatan yang Dapat Dirotasi
6
Atom Berat
35
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Pertanyaan yang Sering Diajukan
This pleuromutilin antibiotic treats community-acquired bacterial pneumonia with activity against multidrug-resistant pathogens.
Yes, Lefamulin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3291398. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 58076382. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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