Levomefolic Acid

CHEMBL1231574 Phase 4 Disetujui Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

459.5 g/mol

LogP

-0.5

Phase

4

The active methylated form of folate, also known as 5-methyltetrahydrofolate (5-MTHF), that does not require enzymatic conversion and is used directly in cellular methylation reactions. It supports brain health and is used in supplements for people with MTHFR gene variants.

Berat Molekul

459,5000 g/mol

LogP

-0,50

TPSA

198,00 Å²

Lipinski RO5

Lulus

Area Terapeutik

Alzheimer's Disease

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Struktur 2D

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SMILES

CN1c2c([nH]c(N)nc2=O)NC[C@@H]1CNc1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1

InChI

InChI=1S/C20H25N7O6/c1-27-12(9-23-16-15(27)18(31)26-20(21)25-16)8-22-11-4-2-10(3-5-11)17(30)24-13(19(32)33)6-7-14(28)29/h2-5,12-13,22H,6-9H2,1H3,(H,24,30)(H,28,29)(H,32,33)(H4,21,23,25,26,31)/t12-,13-/m0/s1

Molecular Formula

C20H25N7O6

HBD / HBA

7 / 10

Ikatan yang Dapat Dirotasi

9

Atom Berat

33

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Pertanyaan yang Sering Diajukan

The active methylated form of folate, also known as 5-methyltetrahydrofolate (5-MTHF), that does not require enzymatic conversion and is used directly in cellular methylation reactions. It supports brain health and is used in supplements for people with MTHFR gene variants.

Yes, Levomefolic Acid is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1231574. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 135398561. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Struktur

Data Cepat

Rumus: C20H25N7O6
Sinonim: 3

Tautan Eksternal

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Penyangkalan Medis

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.