Loncastuximab Tesirine
An antibody-drug conjugate targeting CD19 on malignant B cells, used to treat relapsed or refractory diffuse large B-cell lymphoma and leukemia. It delivers a cytotoxic agent directly to cancer cells while sparing most normal tissues.
Area Terapeutik
Mekanisme Kerja
As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.
HBD / HBA
- / -
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Pertanyaan yang Sering Diajukan
An antibody-drug conjugate targeting CD19 on malignant B cells, used to treat relapsed or refractory diffuse large B-cell lymphoma and leukemia. It delivers a cytotoxic agent directly to cancer cells while sparing most normal tissues.
As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.
Yes, Loncastuximab Tesirine is an approved drug. It has reached clinical phase 4. It is classified as a Antibody drug conjugate.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL4297778. Open-access bioactivity database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.
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