Malathion
An organophosphate compound used medically as a topical treatment for head lice infestations, working by inhibiting acetylcholinesterase in the lice's nervous system to kill both adult lice and their eggs. It is applied directly to dry hair, left for a set period, and then washed out, usually requiring a repeat application after about a week.
Berat Molekul
330,4000 g/mol
LogP
2,40
TPSA
128,00 Ų
Lipinski RO5
Lulus
Mekanisme Kerja
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
Struktur 2D
Cite this structure
Embed this structure
SMILES
CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC
InChI
InChI=1S/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3
Molecular Formula
C10H19O6PS2
HBD / HBA
- / 8
Ikatan yang Dapat Dirotasi
11
Atom Berat
19
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Pertanyaan yang Sering Diajukan
An organophosphate compound used medically as a topical treatment for head lice infestations, working by inhibiting acetylcholinesterase in the lice's nervous system to kill both adult lice and their eggs. It is applied directly to dry hair, left for a set period, and then washed out, usually requiring a repeat application after about a week.
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
Yes, Malathion is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200468. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 4004. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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