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Midazolam

CHEMBL655 Phase 4 Disetujui Small molecule
Half-Life
1.5-2.5 hours
Bioavailability
—
Protein Binding
—
Molecular Weight
325.8 g/mol
LogP
2.5
Phase
4

This short-acting benzodiazepine medication produces sedation, reduces anxiety, and causes temporary memory loss, making it useful for procedural sedation and anesthesia. It acts quickly and wears off relatively fast compared to other medications in its class.

Berat Molekul

325,7670 g/mol

LogP

2,50

TPSA

30,20 Ų

Lipinski RO5

Lulus

Area Terapeutik

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Glaucoma Cardiovascular Disease Respiratory Disease Pain Management Non-Small Cell Lung Cancer Rheumatoid Arthritis Osteoporosis Asthma Chronic Obstructive Pulmonary Disease Alzheimer's Disease Parkinson's Disease Epilepsy Migraine Schizophrenia Bipolar Disorder Generalized Anxiety Disorder Insomnia Infectious Disease Melanoma Oncology Gastroesophageal Reflux Disease Inflammatory Bowel Disease Psoriasis Multiple Sclerosis Chronic Kidney Disease Non-Alcoholic Fatty Liver Disease Stroke Obesity Lymphoma Type 2 Diabetes Hypertension Major Depressive Disorder Breast Cancer Atopic Dermatitis Gout Chronic Pain Hepatitis C Tuberculosis Heart Failure Atrial Fibrillation Prostate Cancer Colorectal Cancer Leukemia

Kelas Obat

N — N - Nervous System

Mekanisme Kerja

Ultra-short-acting benzodiazepine GABA-A receptor positive allosteric modulator.

Pharmacokinetics (PK)

Half-Life 1.5-2.5 hours

Pharmacodynamics (PD)

Mekanisme

Ultra-short-acting benzodiazepine GABA-A receptor positive allosteric modulator.

Struktur 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
Cc1ncc2n1-c1ccc(Cl)cc1C(c1ccccc1F)=NC2

                

                

                
                

                    
InChI

                    
InChI=1S/C18H13ClFN3/c1-11-21-9-13-10-22-18(14-4-2-3-5-16(14)20)15-8-12(19)6-7-17(15)23(11)13/h2-9H,10H2,1H3

                

                

                

                    
                    

                        
Molecular Formula

                        
C18H13ClFN3

                    

                    
                    

                        
HBD / HBA

                        
- / 3

                    

                    
                    

                        
Ikatan yang Dapat Dirotasi

                        
1

                    

                    
                    
                    

                        
Atom Berat

                        
23

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Pertanyaan yang Sering Diajukan

                

                    
                    

                        
                        

                            
This short-acting benzodiazepine medication produces sedation, reduces anxiety, and causes temporary memory loss, making it useful for procedural sedation and anesthesia. It acts quickly and wears off relatively fast compared to other medications in its class.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Ultra-short-acting benzodiazepine GABA-A receptor positive allosteric modulator.

                        

                    

                    

                    
                    

                        
                        

                            
Key pharmacokinetic parameters for Midazolam: Half-life: 1.5-2.5 hours.

                        

                    

                    

                    

                        
                        

                            
Yes, Midazolam is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            
            

                
Related Drugs


                
                

                    
Same Drug Class

                    

                        
                        
                            Acetaminophen
                            Small molecule
                        
                        
                        
                            Aspirin
                            Small molecule
                        
                        
                        
                            Sertraline
                            Small molecule
                        
                        
                        
                            Escitalopram
                            Small molecule
                        
                        
                    

                

                

                
            

            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
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                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL655.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 4192.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Penyangkalan Medis

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.