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Natalizumab

CHEMBL1201607 Phase 4 Disetujui Antibody
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
— g/mol
LogP
—
Phase
4

This monoclonal antibody is given by intravenous infusion to treat relapsing forms of multiple sclerosis and moderate to severe Crohn's disease. It works by preventing immune cells from crossing into the brain, spinal cord, or gut lining, where they would otherwise cause damaging inflammation.

Area Terapeutik

Melanoma Rheumatoid Arthritis Epilepsy Schizophrenia Multiple Sclerosis Stroke

Mekanisme Kerja

As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mekanisme

As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.

HBD / HBA

- / -

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Pertanyaan yang Sering Diajukan

This monoclonal antibody is given by intravenous infusion to treat relapsing forms of multiple sclerosis and moderate to severe Crohn's disease. It works by preventing immune cells from crossing into the brain, spinal cord, or gut lining, where they would otherwise cause damaging inflammation.

As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.

Yes, Natalizumab is an approved drug. It has reached clinical phase 4. It is classified as a Antibody.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201607. Open-access bioactivity database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.

Penyangkalan Medis

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.