Nelfinavir
This protease inhibitor antiviral medication is used as part of combination therapy to treat HIV infection. It works by blocking an enzyme that HIV needs to produce mature, infectious viral particles, thereby reducing the amount of virus in the body.
Berat Molekul
567,8000 g/mol
LogP
5,70
TPSA
127,00 Ų
Lipinski RO5
Gagal
Area Terapeutik
Mekanisme Kerja
Inhibits viral protease, an enzyme essential for cleaving polyprotein precursors into functional viral proteins required for viral maturation and infectivity.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Inhibits viral protease, an enzyme essential for cleaving polyprotein precursors into functional viral proteins required for viral maturation and infectivity.
Struktur 2D
Cite this structure
Embed this structure
SMILES
Cc1c(O)cccc1C(=O)N[C@@H](CSc1ccccc1)[C@H](O)CN1C[C@H]2CCCC[C@H]2C[C@H]1C(=O)NC(C)(C)C
InChI
InChI=1S/C32H45N3O4S/c1-21-25(15-10-16-28(21)36)30(38)33-26(20-40-24-13-6-5-7-14-24)29(37)19-35-18-23-12-9-8-11-22(23)17-27(35)31(39)34-32(2,3)4/h5-7,10,13-16,22-23,26-27,29,36-37H,8-9,11-12,17-20H2,1-4H3,(H,33,38)(H,34,39)/t22-,23+,26-,27-,29+/m0/s1
Molecular Formula
C32H45N3O4S
HBD / HBA
4 / 6
Ikatan yang Dapat Dirotasi
10
Atom Berat
40
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Pertanyaan yang Sering Diajukan
This protease inhibitor antiviral medication is used as part of combination therapy to treat HIV infection. It works by blocking an enzyme that HIV needs to produce mature, infectious viral particles, thereby reducing the amount of virus in the body.
Inhibits viral protease, an enzyme essential for cleaving polyprotein precursors into functional viral proteins required for viral maturation and infectivity.
Yes, Nelfinavir is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL584. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 64143. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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