Netarsudil

CHEMBL4594250 Phase 4 Disetujui Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

453.5 g/mol

LogP

4.6

Phase

4

This eye drop is used to lower elevated pressure inside the eye in patients with open-angle glaucoma or ocular hypertension. It works through a novel mechanism by reducing fluid production in the eye and improving fluid drainage, helping to prevent vision loss.

Berat Molekul

453,5000 g/mol

LogP

4,60

TPSA

94,30 Å²

Lipinski RO5

Lulus

Area Terapeutik

Glaucoma Hypertension

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Struktur 2D

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SMILES

Cc1ccc(C(=O)OCc2ccc([C@@H](CN)C(=O)Nc3ccc4cnccc4c3)cc2)c(C)c1

InChI

InChI=1S/C28H27N3O3/c1-18-3-10-25(19(2)13-18)28(33)34-17-20-4-6-21(7-5-20)26(15-29)27(32)31-24-9-8-23-16-30-12-11-22(23)14-24/h3-14,16,26H,15,17,29H2,1-2H3,(H,31,32)/t26-/m1/s1

Molecular Formula

C28H27N3O3

HBD / HBA

2 / 5

Ikatan yang Dapat Dirotasi

8

Atom Berat

34

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Pertanyaan yang Sering Diajukan

This eye drop is used to lower elevated pressure inside the eye in patients with open-angle glaucoma or ocular hypertension. It works through a novel mechanism by reducing fluid production in the eye and improving fluid drainage, helping to prevent vision loss.

Yes, Netarsudil is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL4594250. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 66599893. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Struktur

Data Cepat

Rumus: C28H27N3O3
Sinonim: 2

Tautan Eksternal

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Penyangkalan Medis

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.