Perhexiline
An antianginal drug used in some countries (particularly Australia) to treat refractory angina by shifting cardiac metabolism from fatty acids to glucose, reducing oxygen demand of the heart muscle. It requires therapeutic drug monitoring due to its variable metabolism and potential for liver and peripheral nerve toxicity.
Berat Molekul
277,5000 g/mol
LogP
6,80
TPSA
12,00 Ų
Lipinski RO5
Lulus
Area Terapeutik
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Struktur 2D
Cite this structure
Embed this structure
SMILES
C1CCC(C(CC2CCCCN2)C2CCCCC2)CC1
InChI
InChI=1S/C19H35N/c1-3-9-16(10-4-1)19(17-11-5-2-6-12-17)15-18-13-7-8-14-20-18/h16-20H,1-15H2
Molecular Formula
C19H35N
HBD / HBA
1 / 1
Ikatan yang Dapat Dirotasi
4
Atom Berat
20
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Pertanyaan yang Sering Diajukan
An antianginal drug used in some countries (particularly Australia) to treat refractory angina by shifting cardiac metabolism from fatty acids to glucose, reducing oxygen demand of the heart muscle. It requires therapeutic drug monitoring due to its variable metabolism and potential for liver and peripheral nerve toxicity.
Yes, Perhexiline is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL75880. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 4746. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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