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Phenacemide

CHEMBL918 Phase 4 Disetujui Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
178.2 g/mol
LogP
0.9
Phase
4

Phenacemide is an anticonvulsant agent of the acylureide class that was historically used in the management of severe, refractory epilepsy, particularly complex partial seizures. Its mechanism involves stabilization of neuronal membranes, though its significant hepatotoxic and psychiatric side effects have led to its discontinuation in most markets.

Berat Molekul

178,1900 g/mol

LogP

0,90

TPSA

72,20 Ų

Lipinski RO5

Lulus

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Struktur 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
NC(=O)NC(=O)Cc1ccccc1

                

                

                
                

                    
InChI

                    
InChI=1S/C9H10N2O2/c10-9(13)11-8(12)6-7-4-2-1-3-5-7/h1-5H,6H2,(H3,10,11,12,13)

                

                

                

                    
                    

                        
Molecular Formula

                        
C9H10N2O2

                    

                    
                    

                        
HBD / HBA

                        
2 / 2

                    

                    
                    

                        
Ikatan yang Dapat Dirotasi

                        
2

                    

                    
                    
                    

                        
Atom Berat

                        
13

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Pertanyaan yang Sering Diajukan

                

                    
                    

                        
                        

                            
Phenacemide is an anticonvulsant agent of the acylureide class that was historically used in the management of severe, refractory epilepsy, particularly complex partial seizures. Its mechanism involves stabilization of neuronal membranes, though its significant hepatotoxic and psychiatric side effects have led to its discontinuation in most markets.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Phenacemide is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL918.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 4753.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Penyangkalan Medis

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.