Piperazine

CHEMBL1412 Phase 4 Disetujui Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

86.1 g/mol

LogP

-1.5

Phase

4

Piperazine is an anthelmintic agent that acts by causing hyperpolarization of Ascaris and Enterobius worm muscle membranes through GABA-mimetic activity, producing flaccid paralysis of the parasite which is then expelled by normal intestinal peristalsis. It has been used for the treatment of roundworm (ascariasis) and pinworm (enterobiasis) infections, and certain piperazine derivatives have demonstrated anticancer activity in preclinical studies.

Berat Molekul

86,1400 g/mol

LogP

-1,50

TPSA

24,10 Å²

Lipinski RO5

Lulus

Area Terapeutik

Melanoma Obesity Breast Cancer Colorectal Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Struktur 2D

SVG PNG

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SMILES

C1CNCCN1

InChI

InChI=1S/C4H10N2/c1-2-6-4-3-5-1/h5-6H,1-4H2

Molecular Formula

C4H10N2

HBD / HBA

2 / 2

Ikatan yang Dapat Dirotasi

0

Atom Berat

6

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Pertanyaan yang Sering Diajukan

Piperazine is an anthelmintic agent that acts by causing hyperpolarization of Ascaris and Enterobius worm muscle membranes through GABA-mimetic activity, producing flaccid paralysis of the parasite which is then expelled by normal intestinal peristalsis. It has been used for the treatment of roundworm (ascariasis) and pinworm (enterobiasis) infections, and certain piperazine derivatives have demonstrated anticancer activity in preclinical studies.

Yes, Piperazine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1412. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 4837. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Struktur

Data Cepat

Rumus: C4H10N2
Sinonim: 6

Tautan Eksternal

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Penyangkalan Medis

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.