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Primaquine Phosphate

CHEMBL43128 Phase 4 Disetujui Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
455.3 g/mol
LogP
—
Phase
4

A phosphate salt form of primaquine with the same therapeutic properties. An antiparasitic medication used to treat and prevent certain types of malaria, particularly to eliminate the dormant liver stages of Plasmodium vivax and Plasmodium ovale that can cause the infection to relapse weeks or months later.

Berat Molekul

455,3400 g/mol

TPSA

216,00 Ų

Area Terapeutik

Malaria

Mekanisme Kerja

Disrupts essential metabolic pathways or structural components of parasitic organisms, leading to paralysis, starvation, or death of the parasite.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mekanisme

Disrupts essential metabolic pathways or structural components of parasitic organisms, leading to paralysis, starvation, or death of the parasite.

Struktur 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
COc1cc(NC(C)CCCN)c2ncccc2c1.O=P(O)(O)O.O=P(O)(O)O

                

                

                
                

                    
InChI

                    
InChI=1S/C15H21N3O.2H3O4P/c1-11(5-3-7-16)18-14-10-13(19-2)9-12-6-4-8-17-15(12)14;2*1-5(2,3)4/h4,6,8-11,18H,3,5,7,16H2,1-2H3;2*(H3,1,2,3,4)

                

                

                

                    
                    

                        
Molecular Formula

                        
C15H27N3O9P2

                    

                    
                    

                        
HBD / HBA

                        
8 / 12

                    

                    
                    

                        
Ikatan yang Dapat Dirotasi

                        
6

                    

                    
                    
                    

                        
Atom Berat

                        
29

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Pertanyaan yang Sering Diajukan

                

                    
                    

                        
                        

                            
A phosphate salt form of primaquine with the same therapeutic properties. An antiparasitic medication used to treat and prevent certain types of malaria, particularly to eliminate the dormant liver stages of Plasmodium vivax and Plasmodium ovale that can cause the infection to relapse weeks or months later.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Disrupts essential metabolic pathways or structural components of parasitic organisms, leading to paralysis, starvation, or death of the parasite.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Primaquine Phosphate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL43128.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 6135.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Penyangkalan Medis

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.