Protamine Sulfate

CHEMBL1201651 Phase 4 Disetujui Unknown

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

— g/mol

LogP

—

Phase

4

Protamine sulfate is a polycationic protein derived from salmon sperm that forms stable ionic complexes with heparin, neutralizing its anticoagulant activity and rapidly reversing heparin-induced anticoagulation. It is used clinically to reverse the anticoagulant effects of unfractionated heparin following cardiovascular surgery, dialysis, and in cases of heparin overdose.

Area Terapeutik

Deep Vein Thrombosis / Pulmonary Embolism Atrial Fibrillation

Pharmacokinetics (PK)

Pharmacodynamics (PD)

HBD / HBA

- / -

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Pertanyaan yang Sering Diajukan

Protamine sulfate is a polycationic protein derived from salmon sperm that forms stable ionic complexes with heparin, neutralizing its anticoagulant activity and rapidly reversing heparin-induced anticoagulation. It is used clinically to reverse the anticoagulant effects of unfractionated heparin following cardiovascular surgery, dialysis, and in cases of heparin overdose.

Yes, Protamine Sulfate is an approved drug. It has reached clinical phase 4. It is classified as a Unknown.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201651. Open-access bioactivity database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.

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Data Cepat

Tautan Eksternal

ChEMBL CHEMBL1201651

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Penyangkalan Medis

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.