Pyridoxine
Pyridoxine (vitamin B6) is a water-soluble vitamin that is converted to its active coenzyme forms pyridoxal-5-phosphate (PLP) and pyridoxamine-5-phosphate, which serve as essential cofactors for over 100 enzymatic reactions in amino acid metabolism, neurotransmitter synthesis, and glycogen catabolism. It is used therapeutically for pyridoxine deficiency states, isoniazid-induced neuropathy, pyridoxine-dependent epilepsy, and nausea of pregnancy.
Berat Molekul
169,1800 g/mol
LogP
-0,80
TPSA
73,60 Ų
Lipinski RO5
Lulus
Area Terapeutik
Mekanisme Kerja
Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.
Struktur 2D
Cite this structure
Embed this structure
SMILES
Cc1ncc(CO)c(CO)c1O
InChI
InChI=1S/C8H11NO3/c1-5-8(12)7(4-11)6(3-10)2-9-5/h2,10-12H,3-4H2,1H3
Molecular Formula
C8H11NO3
HBD / HBA
3 / 4
Ikatan yang Dapat Dirotasi
2
Atom Berat
12
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Pertanyaan yang Sering Diajukan
Pyridoxine (vitamin B6) is a water-soluble vitamin that is converted to its active coenzyme forms pyridoxal-5-phosphate (PLP) and pyridoxamine-5-phosphate, which serve as essential cofactors for over 100 enzymatic reactions in amino acid metabolism, neurotransmitter synthesis, and glycogen catabolism. It is used therapeutically for pyridoxine deficiency states, isoniazid-induced neuropathy, pyridoxine-dependent epilepsy, and nausea of pregnancy.
Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.
Yes, Pyridoxine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1364. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 1054. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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