Revumenib Citrate

CHEMBL6068395 Phase 4 Disetujui Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
841.0 g/mol
LogP
Phase
4

Revumenib citrate is the citrate salt form of revumenib, a menin inhibitor that disrupts the menin-KMT2A interaction to restore normal differentiation in KMT2A-translocated acute leukemia. See revumenib for complete pharmacological details.

Berat Molekul

841,0000 g/mol

TPSA

249,00 Ų

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Struktur 2D

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SMILES

CCN(C(=O)c1cc(F)ccc1Oc1cncnc1N1CC2(CCN(C[C@H]3CC[C@H](NS(=O)(=O)CC)CC3)CC2)C1)C(C)C.O.O=C(O)CC(O)(CC(=O)O)C(=O)O

InChI

InChI=1S/C32H47FN6O4S.C6H8O7.H2O/c1-5-39(23(3)4)31(40)27-17-25(33)9-12-28(27)43-29-18-34-22-35-30(29)38-20-32(21-38)13-15-37(16-14-32)19-24-7-10-26(11-8-24)36-44(41,42)6-2;7-3(8)1-6(13,5(11)12)2-4(9)10;/h9,12,17-18,22-24,26,36H,5-8,10-11,13-16,19-21H2,1-4H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);1H2/t24-,26-;;

Molecular Formula

C38H57FN6O12S

HBD / HBA

6 / 18

Ikatan yang Dapat Dirotasi

16

Atom Berat

58

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Pertanyaan yang Sering Diajukan

Revumenib citrate is the citrate salt form of revumenib, a menin inhibitor that disrupts the menin-KMT2A interaction to restore normal differentiation in KMT2A-translocated acute leukemia. See revumenib for complete pharmacological details.

Yes, Revumenib Citrate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL6068395. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 169490859. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

Penyangkalan Medis

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.