Ropivacaine
A long-acting local anesthetic used for regional anesthesia and pain management during and after surgical procedures, working by blocking sodium channels to prevent nerve signal transmission. It has a lower risk of cardiac toxicity compared to some other local anesthetics, making it a preferred choice for epidural and nerve block anesthesia.
Berat Molekul
274,4000 g/mol
LogP
2,90
TPSA
32,30 Ų
Lipinski RO5
Lulus
Area Terapeutik
Mekanisme Kerja
Blocks voltage-gated sodium channels in nerve cell membranes, preventing the generation and conduction of nerve impulses. This produces reversible loss of sensation in the area of application.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Blocks voltage-gated sodium channels in nerve cell membranes, preventing the generation and conduction of nerve impulses. This produces reversible loss of sensation in the area of application.
Struktur 2D
Cite this structure
Embed this structure
SMILES
CCCN1CCCC[C@H]1C(=O)Nc1c(C)cccc1C
InChI
InChI=1S/C17H26N2O/c1-4-11-19-12-6-5-10-15(19)17(20)18-16-13(2)8-7-9-14(16)3/h7-9,15H,4-6,10-12H2,1-3H3,(H,18,20)/t15-/m0/s1
Molecular Formula
C17H26N2O
HBD / HBA
1 / 2
Ikatan yang Dapat Dirotasi
4
Atom Berat
20
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Pertanyaan yang Sering Diajukan
A long-acting local anesthetic used for regional anesthesia and pain management during and after surgical procedures, working by blocking sodium channels to prevent nerve signal transmission. It has a lower risk of cardiac toxicity compared to some other local anesthetics, making it a preferred choice for epidural and nerve block anesthesia.
Blocks voltage-gated sodium channels in nerve cell membranes, preventing the generation and conduction of nerve impulses. This produces reversible loss of sensation in the area of application.
Yes, Ropivacaine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1077896. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 175805. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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