Simethicone

CHEMBL4297192 Phase 4 Disetujui Unknown

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

238.5 g/mol

LogP

—

Phase

4

Simethicone is an antifoaming agent composed of a mixture of polydimethylsiloxanes and silica gel that reduces surface tension of gas bubbles in the gastrointestinal tract, facilitating their coalescence and expulsion to relieve bloating, flatulence, and gas-associated discomfort. It is pharmacologically inert and not systemically absorbed, acting entirely within the GI lumen. It is widely used as an adjunct in endoscopic procedures to reduce foam interference and as an over-the-counter remedy for gastrointestinal gas.

Berat Molekul

238,4600 g/mol

TPSA

52,60 Å²

Area Terapeutik

Ovarian Cancer Infectious Disease Gastroesophageal Reflux Disease Multiple Sclerosis Chronic Kidney Disease Hypertension Breast Cancer Colorectal Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

SMILES

CO[Si](C)(C)O[Si](C)(C)C.O=[Si]=O

InChI

InChI=1S/C6H18O2Si2.O2Si/c1-7-10(5,6)8-9(2,3)4;1-3-2/h1-6H3;

Molecular Formula

C6H18O4Si3

HBD / HBA

- / 4

Ikatan yang Dapat Dirotasi

3

Atom Berat

13

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Pertanyaan yang Sering Diajukan

Simethicone is an antifoaming agent composed of a mixture of polydimethylsiloxanes and silica gel that reduces surface tension of gas bubbles in the gastrointestinal tract, facilitating their coalescence and expulsion to relieve bloating, flatulence, and gas-associated discomfort. It is pharmacologically inert and not systemically absorbed, acting entirely within the GI lumen. It is widely used as an adjunct in endoscopic procedures to reduce foam interference and as an over-the-counter remedy for gastrointestinal gas.

Yes, Simethicone is an approved drug. It has reached clinical phase 4. It is classified as a Unknown.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL4297192. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 6433516. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Data Cepat

Rumus: C6H18O4Si3
Sinonim: 212

Tautan Eksternal

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Penyangkalan Medis

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.