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Sitagliptin Phosphate

CHEMBL1201174 Phase 4 Disetujui Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
523.3 g/mol
LogP
—
Phase
4

A phosphate salt form of sitagliptin with the same therapeutic properties. This once-daily pill helps control blood sugar in type 2 diabetes by preventing the breakdown of incretin hormones that naturally stimulate insulin release after eating.

Berat Molekul

523,3200 g/mol

TPSA

156,00 Ų

Area Terapeutik

Benign Prostatic Hyperplasia Cardiovascular Disease Rheumatoid Arthritis Osteoporosis Psoriasis Chronic Kidney Disease Non-Alcoholic Fatty Liver Disease Stroke Hyperlipidemia Obesity Lymphoma Type 2 Diabetes Hypertension Hepatitis C Heart Failure Colorectal Cancer Leukemia

Mekanisme Kerja

DPP-4 inhibitor increasing incretin levels.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mekanisme

DPP-4 inhibitor increasing incretin levels.

Struktur 2D

SVG PNG

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SMILES

                    
N[C@@H](CC(=O)N1CCn2c(nnc2C(F)(F)F)C1)Cc1cc(F)c(F)cc1F.O.O=P(O)(O)O

                

                

                
                

                    
InChI

                    
InChI=1S/C16H15F6N5O.H3O4P.H2O/c17-10-6-12(19)11(18)4-8(10)3-9(23)5-14(28)26-1-2-27-13(7-26)24-25-15(27)16(20,21)22;1-5(2,3)4;/h4,6,9H,1-3,5,7,23H2;(H3,1,2,3,4);1H2/t9-;;/m1../s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C16H20F6N5O6P

                    

                    
                    

                        
HBD / HBA

                        
5 / 15

                    

                    
                    

                        
Ikatan yang Dapat Dirotasi

                        
4

                    

                    
                    
                    

                        
Atom Berat

                        
34

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Pertanyaan yang Sering Diajukan

                

                    
                    

                        
                        

                            
A phosphate salt form of sitagliptin with the same therapeutic properties. This once-daily pill helps control blood sugar in type 2 diabetes by preventing the breakdown of incretin hormones that naturally stimulate insulin release after eating.

                        

                    

                    

                    

                    
                    

                        
                        

                            
DPP-4 inhibitor increasing incretin levels.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Sitagliptin Phosphate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1201174.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 11591741.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Penyangkalan Medis

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.