Sonidegib Phosphate

CHEMBL3137317 Phase 4 Disetujui Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

681.5 g/mol

LogP

—

Phase

4

A phosphate salt form of sonidegib with the same therapeutic properties. By blocking the Hedgehog signaling pathway that drives tumor cell growth, this oral targeted therapy is used for advanced or recurrent basal cell carcinoma when surgery or radiation is not appropriate.

Berat Molekul

681,5000 g/mol

TPSA

219,00 Å²

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Struktur 2D

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SMILES

Cc1c(C(=O)Nc2ccc(N3C[C@@H](C)O[C@@H](C)C3)nc2)cccc1-c1ccc(OC(F)(F)F)cc1.O=P(O)(O)O.O=P(O)(O)O

InChI

InChI=1S/C26H26F3N3O3.2H3O4P/c1-16-14-32(15-17(2)34-16)24-12-9-20(13-30-24)31-25(33)23-6-4-5-22(18(23)3)19-7-10-21(11-8-19)35-26(27,28)29;2*1-5(2,3)4/h4-13,16-17H,14-15H2,1-3H3,(H,31,33);2*(H3,1,2,3,4)/t16-,17+;;

Molecular Formula

C26H32F3N3O11P2

HBD / HBA

7 / 16

Ikatan yang Dapat Dirotasi

5

Atom Berat

45

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Pertanyaan yang Sering Diajukan

A phosphate salt form of sonidegib with the same therapeutic properties. By blocking the Hedgehog signaling pathway that drives tumor cell growth, this oral targeted therapy is used for advanced or recurrent basal cell carcinoma when surgery or radiation is not appropriate.

Yes, Sonidegib Phosphate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3137317. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 45138699. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Struktur

Data Cepat

Rumus: C26H32F3N3O11P2

Tautan Eksternal

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Penyangkalan Medis

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.