Technetium Tc 99M Sulfur Colloid

CHEMBL1201529 Phase 4 Disetujui Unknown
Half-Life
Bioavailability
Protein Binding
Molecular Weight
355.4 g/mol
LogP
Phase
4

Technetium Tc 99m sulfur colloid is a radiolabeled colloidal particle preparation that is phagocytosed by reticuloendothelial cells (Kupffer cells in the liver, spleen, and bone marrow), used for liver-spleen scintigraphy, bone marrow imaging, and sentinel lymph node mapping in breast cancer and melanoma. The particle size determines the biodistribution: larger particles concentrate in the liver and spleen, while filtered smaller particles enable gastrointestinal transit and lymphoscintigraphy. It is widely used for sentinel node biopsy guidance in surgical oncology.

Berat Molekul

355,4000 g/mol

TPSA

202,00 Ų

Area Terapeutik

Pharmacokinetics (PK)

Pharmacodynamics (PD)

SMILES

S1SSSSSSS1.[99Tc]

InChI

InChI=1S/S8.Tc/c1-2-4-6-8-7-5-3-1;/i;1+1

Molecular Formula

S8Tc

HBD / HBA

- / 8

Ikatan yang Dapat Dirotasi

0

Atom Berat

9

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Pertanyaan yang Sering Diajukan

Technetium Tc 99m sulfur colloid is a radiolabeled colloidal particle preparation that is phagocytosed by reticuloendothelial cells (Kupffer cells in the liver, spleen, and bone marrow), used for liver-spleen scintigraphy, bone marrow imaging, and sentinel lymph node mapping in breast cancer and melanoma. The particle size determines the biodistribution: larger particles concentrate in the liver and spleen, while filtered smaller particles enable gastrointestinal transit and lymphoscintigraphy. It is widely used for sentinel node biopsy guidance in surgical oncology.

Yes, Technetium Tc 99M Sulfur Colloid is an approved drug. It has reached clinical phase 4. It is classified as a Unknown.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201529. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 76957057. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

Penyangkalan Medis

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.