Thiopental

CHEMBL441 Phase 4 Disetujui Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

242.3 g/mol

LogP

2.9

Phase

4

This fast-acting barbiturate has been used as an intravenous anesthetic to induce unconsciousness before surgery and in emergency settings such as controlling severe seizures or reducing brain swelling. It works by enhancing the effects of GABA, a calming neurotransmitter in the brain. Its use has largely been replaced by newer anesthetic agents in many countries.

Berat Molekul

242,3400 g/mol

LogP

2,90

TPSA

90,30 Å²

Lipinski RO5

Lulus

Area Terapeutik

Pancreatic Cancer Glaucoma Age-Related Macular Degeneration Pain Management Generalized Anxiety Disorder Gastroesophageal Reflux Disease Obesity Hypertension Breast Cancer Chronic Pain

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Struktur 2D

SVG PNG

Cite this structure

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SMILES

CCCC(C)C1(CC)C(=O)NC(=S)NC1=O

InChI

InChI=1S/C11H18N2O2S/c1-4-6-7(3)11(5-2)8(14)12-10(16)13-9(11)15/h7H,4-6H2,1-3H3,(H2,12,13,14,15,16)

Molecular Formula

C11H18N2O2S

HBD / HBA

2 / 3

Ikatan yang Dapat Dirotasi

4

Atom Berat

16

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Pertanyaan yang Sering Diajukan

This fast-acting barbiturate has been used as an intravenous anesthetic to induce unconsciousness before surgery and in emergency settings such as controlling severe seizures or reducing brain swelling. It works by enhancing the effects of GABA, a calming neurotransmitter in the brain. Its use has largely been replaced by newer anesthetic agents in many countries.

Yes, Thiopental is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL441. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 3000715. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Thiopental di PillFYI

Struktur

Data Cepat

Rumus: C11H18N2O2S

Tautan Eksternal

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Penyangkalan Medis

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.