Tigecycline

CHEMBL376140 Phase 4 Disetujui Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

585.6 g/mol

LogP

1.1

Phase

4

This broad-spectrum antibiotic is given intravenously in hospital settings to treat serious infections including complicated skin infections, abdominal infections, and community-acquired pneumonia caused by bacteria resistant to other antibiotics. It belongs to the glycylcycline class and works by blocking bacterial protein synthesis. It carries a boxed warning for increased risk of death in some settings compared to other antibiotics.

Berat Molekul

585,6000 g/mol

LogP

1,10

TPSA

206,00 Å²

Lipinski RO5

Gagal

Area Terapeutik

Infectious Disease Obesity Leukemia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Struktur 2D

SVG PNG

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SMILES

CN(C)c1cc(NC(=O)CNC(C)(C)C)c(O)c2c1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]3(O)C(O)=C1C2=O

InChI

InChI=1S/C29H39N5O8/c1-28(2,3)31-11-17(35)32-15-10-16(33(4)5)13-8-12-9-14-21(34(6)7)24(38)20(27(30)41)26(40)29(14,42)25(39)18(12)23(37)19(13)22(15)36/h10,12,14,21,31,36,38-39,42H,8-9,11H2,1-7H3,(H2,30,41)(H,32,35)/t12-,14-,21-,29-/m0/s1

Molecular Formula

C29H39N5O8

HBD / HBA

7 / 11

Ikatan yang Dapat Dirotasi

7

Atom Berat

42

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Pertanyaan yang Sering Diajukan

This broad-spectrum antibiotic is given intravenously in hospital settings to treat serious infections including complicated skin infections, abdominal infections, and community-acquired pneumonia caused by bacteria resistant to other antibiotics. It belongs to the glycylcycline class and works by blocking bacterial protein synthesis. It carries a boxed warning for increased risk of death in some settings compared to other antibiotics.

Yes, Tigecycline is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL376140. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 54686904. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Tigecycline di PillFYI

Struktur

Data Cepat

Rumus: C29H39N5O8
Sinonim: 1

Tautan Eksternal

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Penyangkalan Medis

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.