Trientine Hydrochloride

CHEMBL3989777 Phase 4 Disetujui Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
219.2 g/mol
LogP
Phase
4

Trientine hydrochloride is the hydrochloride salt form of trientine, a copper-chelating agent used for Wilson's disease and under investigation as an anti-fibrotic agent in melanoma through copper-dependent pathways. See trientine for complete pharmacological details. This salt formulation is used in approved oral capsule preparations.

Berat Molekul

219,1500 g/mol

TPSA

76,10 Ų

Area Terapeutik

Mekanisme Kerja

Forms stable, water-soluble chelate complexes with specific metal ions, facilitating their excretion from the body through the kidneys. This reduces toxic metal burden in affected tissues.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mekanisme

Forms stable, water-soluble chelate complexes with specific metal ions, facilitating their excretion from the body through the kidneys. This reduces toxic metal burden in affected tissues.

Struktur 2D

SVG PNG

Cite this structure


                        

Embed this structure


                        

SMILES

Cl.Cl.NCCNCCNCCN

InChI

InChI=1S/C6H18N4.2ClH/c7-1-3-9-5-6-10-4-2-8;;/h9-10H,1-8H2;2*1H

Molecular Formula

C6H20Cl2N4

HBD / HBA

6 / 4

Ikatan yang Dapat Dirotasi

7

Atom Berat

12

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Pertanyaan yang Sering Diajukan

Trientine hydrochloride is the hydrochloride salt form of trientine, a copper-chelating agent used for Wilson's disease and under investigation as an anti-fibrotic agent in melanoma through copper-dependent pathways. See trientine for complete pharmacological details. This salt formulation is used in approved oral capsule preparations.

Forms stable, water-soluble chelate complexes with specific metal ions, facilitating their excretion from the body through the kidneys. This reduces toxic metal burden in affected tissues.

Yes, Trientine Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3989777. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 71433. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

Penyangkalan Medis

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.