Trihexyphenidyl Hydrochloride
Trihexyphenidyl hydrochloride is an anticholinergic agent that blocks muscarinic receptors in the central and peripheral nervous system, reducing excess cholinergic activity. It is primarily used to treat Parkinson's disease and drug-induced extrapyramidal symptoms by restoring dopamine-acetylcholine balance. Its salt form provides improved stability and bioavailability for oral administration.
Berat Molekul
337,9000 g/mol
TPSA
23,50 Ų
Area Terapeutik
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Struktur 2D
Cite this structure
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SMILES
Cl.OC(CCN1CCCCC1)(c1ccccc1)C1CCCCC1
InChI
InChI=1S/C20H31NO.ClH/c22-20(18-10-4-1-5-11-18,19-12-6-2-7-13-19)14-17-21-15-8-3-9-16-21;/h1,4-5,10-11,19,22H,2-3,6-9,12-17H2;1H
Molecular Formula
C20H32ClNO
HBD / HBA
2 / 2
Ikatan yang Dapat Dirotasi
5
Atom Berat
23
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Pertanyaan yang Sering Diajukan
Trihexyphenidyl hydrochloride is an anticholinergic agent that blocks muscarinic receptors in the central and peripheral nervous system, reducing excess cholinergic activity. It is primarily used to treat Parkinson's disease and drug-induced extrapyramidal symptoms by restoring dopamine-acetylcholine balance. Its salt form provides improved stability and bioavailability for oral administration.
Yes, Trihexyphenidyl Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1092. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 66007. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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