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Adefovir Dipivoxil

CHEMBL922 Phase 4 承認済み Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
501.5 g/mol
LogP
1.8
Phase
4

An oral antiviral medication used to treat chronic hepatitis B infection by blocking the enzyme the hepatitis B virus uses to copy its DNA, suppressing viral replication in the liver. It is taken once daily and is particularly useful for patients whose hepatitis B has become resistant to lamivudine. Long-term use requires monitoring of kidney function, as the drug can affect the kidneys at higher doses.

分子量

501.5000 g/mol

LogP

1.80

TPSA

167.00 Ų

リピンスキーの五則

不適合

治療領域

Hypertension Hepatitis C

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D構造

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
CC(C)(C)C(=O)OCOP(=O)(COCCn1cnc2c(N)ncnc21)OCOC(=O)C(C)(C)C

                

                

                
                

                    
InChI

                    
InChI=1S/C20H32N5O8P/c1-19(2,3)17(26)30-11-32-34(28,33-12-31-18(27)20(4,5)6)13-29-8-7-25-10-24-14-15(21)22-9-23-16(14)25/h9-10H,7-8,11-13H2,1-6H3,(H2,21,22,23)

                

                

                

                    
                    

                        
Molecular Formula

                        
C20H32N5O8P

                    

                    
                    

                        
HBD / HBA

                        
1 / 12

                    

                    
                    

                        
回転可能結合数

                        
15

                    

                    
                    
                    

                        
重原子数

                        
34

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
よくある質問

                

                    
                    

                        
                        

                            
An oral antiviral medication used to treat chronic hepatitis B infection by blocking the enzyme the hepatitis B virus uses to copy its DNA, suppressing viral replication in the liver. It is taken once daily and is particularly useful for patients whose hepatitis B has become resistant to lamivudine. Long-term use requires monitoring of kidney function, as the drug can affect the kidneys at higher doses.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Adefovir Dipivoxil is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL922.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 60871.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
医学的免責事項

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.