Alprostadil
A synthetic form of prostaglandin E1 that relaxes smooth muscle in blood vessels and is used to treat erectile dysfunction by increasing blood flow to the penis, and also to keep the ductus arteriosus open in newborns with certain congenital heart defects until surgery can be performed. It can be administered by penile injection, urethral suppository, or intravenously depending on the condition being treated.
分子量
354.5000 g/mol
LogP
3.20
TPSA
94.80 Ų
リピンスキーの五則
適合
治療領域
Pharmacokinetics (PK)
Pharmacodynamics (PD)
2D構造
Cite this structure
Embed this structure
SMILES
CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)O
InChI
InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,19+/m0/s1
Molecular Formula
C20H34O5
HBD / HBA
3 / 5
回転可能結合数
13
重原子数
25
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
よくある質問
A synthetic form of prostaglandin E1 that relaxes smooth muscle in blood vessels and is used to treat erectile dysfunction by increasing blood flow to the penis, and also to keep the ductus arteriosus open in newborns with certain congenital heart defects until surgery can be performed. It can be administered by penile injection, urethral suppository, or intravenously depending on the condition being treated.
Yes, Alprostadil is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL495. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 5280723. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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