Betaine
Methyl group donation is the metabolic function of betaine, a naturally occurring compound that participates in the pathways regulating homocysteine concentration. Its therapeutic application is homocystinuria, a rare inherited disorder of metabolism in which homocysteine accumulates; supplying an alternative methyl donor allows remethylation of homocysteine and lowers the circulating burden. The same compound occurs in ordinary foods, notably beets and whole grains, and has been examined for possible effects on hepatic and cardiovascular health outside the inherited disorder. Its small size is notable even among small-molecule drugs: the formula is C5H11NO2 and the molecular weight approximately 117.2 g/mol. The agent is approved and completed the final phase of clinical development.
A naturally occurring compound that serves as a methyl donor in several metabolic pathways, including those that regulate homocysteine levels. It is used medically to treat homocystinuria, a rare inherited metabolic disorder. It is also found naturally in beets and whole grains and is studied for liver and cardiovascular health.
分子量
117.1500 g/mol
LogP
0.50
TPSA
40.10 Ų
リピンスキーの五則
適合
Pharmacokinetics (PK)
Pharmacodynamics (PD)
2D構造
Cite this structure
Embed this structure
SMILES
C[N+](C)(C)CC(=O)O
InChI
InChI=1S/C5H11NO2/c1-6(2,3)4-5(7)8/h4H2,1-3H3/p+1
Molecular Formula
C5H11NO2
HBD / HBA
- / 2
回転可能結合数
1
重原子数
8
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
よくある質問
A naturally occurring compound that serves as a methyl donor in several metabolic pathways, including those that regulate homocysteine levels. It is used medically to treat homocystinuria, a rare inherited metabolic disorder. It is also found naturally in beets and whole grains and is studied for liver and cardiovascular health.
Yes, Betaine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL95889. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 247. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-08-20.
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