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Brimonidine

CHEMBL844 Phase 4 承認済み Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
292.1 g/mol
LogP
0.6
Phase
4

An alpha-2 adrenergic agonist used primarily as eye drops to lower intraocular pressure in open-angle glaucoma and ocular hypertension. It reduces aqueous humor production and increases drainage from the eye. A topical gel formulation is also used for temporary reduction of persistent facial redness in rosacea.

分子量

292.1300 g/mol

LogP

0.60

TPSA

62.20 Ų

リピンスキーの五則

適合

治療領域

Ovarian Cancer Glaucoma Age-Related Macular Degeneration Systemic Lupus Erythematosus Multiple Sclerosis Obesity Hypertension Breast Cancer Cardiovascular Disease Prostate Cancer

作用機序

Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

機序

Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

2D構造

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
Brc1c(NC2=NCCN2)ccc2nccnc12

                

                

                
                

                    
InChI

                    
InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17)

                

                

                

                    
                    

                        
Molecular Formula

                        
C11H10BrN5

                    

                    
                    

                        
HBD / HBA

                        
2 / 3

                    

                    
                    

                        
回転可能結合数

                        
2

                    

                    
                    
                    

                        
重原子数

                        
17

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
よくある質問

                

                    
                    

                        
                        

                            
An alpha-2 adrenergic agonist used primarily as eye drops to lower intraocular pressure in open-angle glaucoma and ocular hypertension. It reduces aqueous humor production and increases drainage from the eye. A topical gel formulation is also used for temporary reduction of persistent facial redness in rosacea.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Brimonidine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL844.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 2435.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
医学的免責事項

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.