Calcium Metrizoate
Iodine content is what makes calcium metrizoate visible on radiography: the compound pairs calcium with metrizoic acid to produce an ionic iodinated contrast medium whose atoms absorb X-rays strongly. Injection into blood vessels or body cavities therefore renders those structures visible against surrounding soft tissue. Historical angiographic and cavity studies relied on agents of this type before non-ionic media became available. Because ionic contrast media carry a higher osmolality and a less favourable tolerability profile, safer non-ionic agents have largely superseded them. The compound is recorded with the formula C24H20CaI6N4O8 and a formula mass near 1293.9 g/mol, its development having reached the final clinical phase.
A contrast agent combining calcium with metrizoic acid, historically used for imaging of blood vessels and body cavities by X-ray. It is an ionic iodinated contrast medium that allows visualization of internal structures. It has largely been superseded by safer non-ionic contrast agents.
分子量
1293.9000 g/mol
TPSA
179.00 Ų
作用機序
Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.
2D構造
Cite this structure
Embed this structure
SMILES
CC(=O)Nc1c(I)c(C(=O)[O-])c(I)c(N(C)C(C)=O)c1I.CC(=O)Nc1c(I)c(C(=O)[O-])c(I)c(N(C)C(C)=O)c1I.[Ca+2]
InChI
InChI=1S/2C12H11I3N2O4.Ca/c2*1-4(18)16-10-7(13)6(12(20)21)8(14)11(9(10)15)17(3)5(2)19;/h2*1-3H3,(H,16,18)(H,20,21);/q;;+2/p-2
Molecular Formula
C24H20CaI6N4O8
HBD / HBA
2 / 8
回転可能結合数
4
重原子数
43
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
よくある質問
A contrast agent combining calcium with metrizoic acid, historically used for imaging of blood vessels and body cavities by X-ray. It is an ionic iodinated contrast medium that allows visualization of internal structures. It has largely been superseded by safer non-ionic contrast agents.
Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.
Yes, Calcium Metrizoate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2068723. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 10418946. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-08-20.
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