Canagliflozin Anhydrous
The anhydrous form of canagliflozin, an SGLT2 inhibitor used for blood sugar management in type 2 diabetes with additional cardiovascular and renal benefits. This non-hydrated salt form is used in specific pharmaceutical formulations for stability. It shares the same mechanism and clinical profile as the standard canagliflozin formulation.
分子量
444.5000 g/mol
LogP
3.20
TPSA
118.00 Ų
リピンスキーの五則
適合
作用機序
Selectively inhibits sodium-glucose cotransporter 2 (SGLT2) in the proximal renal tubule, reducing glucose reabsorption and promoting urinary glucose excretion. This lowers blood glucose levels independently of insulin secretion.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Selectively inhibits sodium-glucose cotransporter 2 (SGLT2) in the proximal renal tubule, reducing glucose reabsorption and promoting urinary glucose excretion. This lowers blood glucose levels independently of insulin secretion.
2D構造
Cite this structure
Embed this structure
SMILES
Cc1ccc([C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1Cc1ccc(-c2ccc(F)cc2)s1
InChI
InChI=1S/C24H25FO5S/c1-13-2-3-15(24-23(29)22(28)21(27)19(12-26)30-24)10-16(13)11-18-8-9-20(31-18)14-4-6-17(25)7-5-14/h2-10,19,21-24,26-29H,11-12H2,1H3/t19-,21-,22+,23-,24+/m1/s1
Molecular Formula
C24H25FO5S
HBD / HBA
4 / 7
回転可能結合数
5
重原子数
31
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
よくある質問
The anhydrous form of canagliflozin, an SGLT2 inhibitor used for blood sugar management in type 2 diabetes with additional cardiovascular and renal benefits. This non-hydrated salt form is used in specific pharmaceutical formulations for stability. It shares the same mechanism and clinical profile as the standard canagliflozin formulation.
Selectively inhibits sodium-glucose cotransporter 2 (SGLT2) in the proximal renal tubule, reducing glucose reabsorption and promoting urinary glucose excretion. This lowers blood glucose levels independently of insulin secretion.
Yes, Canagliflozin Anhydrous is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2048484. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 24812758. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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