Cenegermin
A recombinant form of human nerve growth factor administered as eye drops to treat neurotrophic keratitis, a rare corneal disease caused by impaired nerve supply to the eye. By supporting corneal nerve regeneration and epithelial healing, it addresses the underlying pathology rather than just symptoms. It represents the first topical treatment specifically targeting the neurological cause of this condition.
治療領域
作用機序
As a recombinant protein, it replicates the function of the naturally occurring human protein, supplementing or replacing deficient endogenous production to restore normal physiological activity.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
As a recombinant protein, it replicates the function of the naturally occurring human protein, supplementing or replacing deficient endogenous production to restore normal physiological activity.
HBD / HBA
- / -
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
よくある質問
A recombinant form of human nerve growth factor administered as eye drops to treat neurotrophic keratitis, a rare corneal disease caused by impaired nerve supply to the eye. By supporting corneal nerve regeneration and epithelial healing, it addresses the underlying pathology rather than just symptoms. It represents the first topical treatment specifically targeting the neurological cause of this condition.
As a recombinant protein, it replicates the function of the naturally occurring human protein, supplementing or replacing deficient endogenous production to restore normal physiological activity.
Yes, Cenegermin is an approved drug. It has reached clinical phase 4. It is classified as a Protein.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL4297852. Open-access bioactivity database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.
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