Dimethyl Fumarate
An oral medication used to treat relapsing forms of multiple sclerosis and moderate-to-severe psoriasis by activating the Nrf2 pathway, which reduces oxidative stress and has anti-inflammatory effects. In multiple sclerosis, it reduces the frequency of relapses and slows disability progression. Flushing and gastrointestinal side effects are common early in treatment, and patients require monitoring of lymphocyte counts.
分子量
144.1200 g/mol
LogP
0.70
TPSA
52.60 Ų
リピンスキーの五則
適合
治療領域
Pharmacokinetics (PK)
Pharmacodynamics (PD)
2D構造
Cite this structure
Embed this structure
SMILES
COC(=O)/C=C/C(=O)OC
InChI
InChI=1S/C6H8O4/c1-9-5(7)3-4-6(8)10-2/h3-4H,1-2H3/b4-3+
Molecular Formula
C6H8O4
HBD / HBA
- / 4
回転可能結合数
4
重原子数
10
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
よくある質問
An oral medication used to treat relapsing forms of multiple sclerosis and moderate-to-severe psoriasis by activating the Nrf2 pathway, which reduces oxidative stress and has anti-inflammatory effects. In multiple sclerosis, it reduces the frequency of relapses and slows disability progression. Flushing and gastrointestinal side effects are common early in treatment, and patients require monitoring of lymphocyte counts.
Yes, Dimethyl Fumarate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2107333. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 637568. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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