Dipyrone

CHEMBL3989803 Phase 4 承認済み Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

333.3 g/mol

LogP

—

Phase

4

Also known as metamizole, a non-opioid analgesic and antipyretic used for pain and fever that is not adequately controlled by other medications, including postoperative and cancer pain. It works by blocking prostaglandin synthesis and activating endogenous pain inhibition pathways. Due to a rare but serious risk of agranulocytosis (dangerous drop in white blood cells), it is banned in some countries including the United States.

分子量

333.3400 g/mol

TPSA

92.40 Å²

治療領域

Pain Management Migraine Generalized Anxiety Disorder Infectious Disease Non-Alcoholic Fatty Liver Disease Stroke Obesity Gastroenterology Hypertension Chronic Pain

作用機序

Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission and modulates the emotional response to pain.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

機序

Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission …

2D構造

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SMILES

Cc1c(N(C)CS(=O)(=O)[O-])c(=O)n(-c2ccccc2)n1C.O.[Na+]

InChI

InChI=1S/C13H17N3O4S.Na.H2O/c1-10-12(14(2)9-21(18,19)20)13(17)16(15(10)3)11-7-5-4-6-8-11;;/h4-8H,9H2,1-3H3,(H,18,19,20);;1H2/q;+1;/p-1

Molecular Formula

C13H16N3NaO4S

HBD / HBA

- / 6

回転可能結合数

4

重原子数

22

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

よくある質問

Also known as metamizole, a non-opioid analgesic and antipyretic used for pain and fever that is not adequately controlled by other medications, including postoperative and cancer pain. It works by blocking prostaglandin synthesis and activating endogenous pain inhibition pathways. Due to a rare but serious risk of agranulocytosis (dangerous drop in white blood cells), it is banned in some countries including the United States.

Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission and modulates the emotional response to pain.

Yes, Dipyrone is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3989803. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 522325. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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分子式: C13H16N3NaO4S

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医学的免責事項

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.