Ethotoin
This hydantoin anticonvulsant stabilizes nerve cell membranes to reduce the spread of abnormal electrical activity that causes seizures. It is used to treat certain types of epilepsy when other medications are not suitable.
分子量
204.2200 g/mol
LogP
1.00
TPSA
49.40 Ų
リピンスキーの五則
適合
作用機序
Modulates neuronal excitability through one or more mechanisms including blockade of voltage-gated sodium channels, enhancement of GABAergic inhibition, or modulation of calcium channels. This reduces the frequency and severity of seizure activity.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Modulates neuronal excitability through one or more mechanisms including blockade of voltage-gated sodium channels, enhancement of GABAergic inhibition, or modulation of calcium channels. This reduces the frequency and severity of …
2D構造
Cite this structure
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SMILES
CCN1C(=O)NC(c2ccccc2)C1=O
InChI
InChI=1S/C11H12N2O2/c1-2-13-10(14)9(12-11(13)15)8-6-4-3-5-7-8/h3-7,9H,2H2,1H3,(H,12,15)
Molecular Formula
C11H12N2O2
HBD / HBA
1 / 2
回転可能結合数
2
重原子数
15
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
よくある質問
This hydantoin anticonvulsant stabilizes nerve cell membranes to reduce the spread of abnormal electrical activity that causes seizures. It is used to treat certain types of epilepsy when other medications are not suitable.
Modulates neuronal excitability through one or more mechanisms including blockade of voltage-gated sodium channels, enhancement of GABAergic inhibition, or modulation of calcium channels. This reduces the frequency and severity of seizure activity.
Yes, Ethotoin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1095. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 3292. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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