Florbetapir F 18
This radioactive imaging agent binds to beta-amyloid plaques in the brain and is used with PET scanning to help diagnose Alzheimer's disease. It provides visual information about amyloid burden that can support clinical evaluation in patients with cognitive impairment.
分子量
359.4000 g/mol
LogP
3.50
TPSA
52.60 Ų
リピンスキーの五則
適合
治療領域
Pharmacokinetics (PK)
Pharmacodynamics (PD)
2D構造
Cite this structure
Embed this structure
SMILES
CNc1ccc(/C=C/c2ccc(OCCOCCOCC[18F])nc2)cc1
InChI
InChI=1S/C20H25FN2O3/c1-22-19-7-4-17(5-8-19)2-3-18-6-9-20(23-16-18)26-15-14-25-13-12-24-11-10-21/h2-9,16,22H,10-15H2,1H3/b3-2+/i21-1
Molecular Formula
C20H25FN2O3
HBD / HBA
1 / 6
回転可能結合数
12
重原子数
26
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
よくある質問
This radioactive imaging agent binds to beta-amyloid plaques in the brain and is used with PET scanning to help diagnose Alzheimer's disease. It provides visual information about amyloid burden that can support clinical evaluation in patients with cognitive impairment.
Yes, Florbetapir F 18 is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1774461. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 24822371. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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