Flurazepam
A benzodiazepine medication prescribed for the short-term treatment of insomnia, helping patients fall asleep faster and stay asleep longer by enhancing the activity of GABA, a calming brain chemical. Due to its long half-life, it may cause next-day drowsiness and impair coordination. It carries a risk of dependence and is not recommended for long-term use.
分子量
387.9000 g/mol
LogP
3.00
TPSA
35.90 Ų
リピンスキーの五則
適合
治療領域
作用機序
Enhances the effect of gamma-aminobutyric acid (GABA) at GABA-A receptors by binding to an allosteric site and increasing the frequency of chloride ion channel opening. This produces anxiolytic, sedative, hypnotic, and anticonvulsant effects.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Enhances the effect of gamma-aminobutyric acid (GABA) at GABA-A receptors by binding to an allosteric site and increasing the frequency of chloride ion channel opening. This produces anxiolytic, sedative, hypnotic, …
2D構造
Cite this structure
Embed this structure
SMILES
CCN(CC)CCN1C(=O)CN=C(c2ccccc2F)c2cc(Cl)ccc21
InChI
InChI=1S/C21H23ClFN3O/c1-3-25(4-2)11-12-26-19-10-9-15(22)13-17(19)21(24-14-20(26)27)16-7-5-6-8-18(16)23/h5-10,13H,3-4,11-12,14H2,1-2H3
Molecular Formula
C21H23ClFN3O
HBD / HBA
- / 4
回転可能結合数
6
重原子数
27
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
よくある質問
A benzodiazepine medication prescribed for the short-term treatment of insomnia, helping patients fall asleep faster and stay asleep longer by enhancing the activity of GABA, a calming brain chemical. Due to its long half-life, it may cause next-day drowsiness and impair coordination. It carries a risk of dependence and is not recommended for long-term use.
Enhances the effect of gamma-aminobutyric acid (GABA) at GABA-A receptors by binding to an allosteric site and increasing the frequency of chloride ion channel opening. This produces anxiolytic, sedative, hypnotic, and anticonvulsant effects.
Yes, Flurazepam is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL968. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 3393. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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