Gallium Ga 68 Gozetotide
This radioactive diagnostic agent is used in PET imaging to detect prostate cancer that has spread or recurred. It binds to prostate-specific membrane antigen (PSMA), a protein highly expressed on prostate cancer cells, allowing the imaging device to locate even small deposits of cancer. It is particularly useful when conventional imaging may not detect disease recurrence.
分子量
1011.9000 g/mol
TPSA
381.00 Ų
治療領域
作用機序
Functions as a diagnostic agent by providing contrast enhancement or radioactive tracer activity that enables visualization of anatomical structures or physiological processes during medical imaging.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Functions as a diagnostic agent by providing contrast enhancement or radioactive tracer activity that enables visualization of anatomical structures or physiological processes during medical imaging.
2D構造
Cite this structure
Embed this structure
SMILES
O=C([O-])CN(CCN(CC(=O)[O-])Cc1cc(CCC(=O)NCCCCCC(=O)NCCCC[C@H](NC(=O)N[C@@H](CCC(=O)O)C(=O)O)C(=O)O)ccc1[O-])Cc1cc(CCC(=O)O)ccc1[O-].[68Ga+3].[OH3+]
InChI
InChI=1S/C44H62N6O17.Ga.H2O/c51-34-13-8-28(22-30(34)24-49(26-40(59)60)20-21-50(27-41(61)62)25-31-23-29(9-14-35(31)52)11-16-38(55)56)10-15-37(54)46-18-4-1-2-7-36(53)45-19-5-3-6-32(42(63)64)47-44(67)48-33(43(65)66)12-17-39(57)58;;/h8-9,13-14,22-23,32-33,51-52H,1-7,10-12,15-21,24-27H2,(H,45,53)(H,46,54)(H,55,56)(H,57,58)(H,59,60)(H,61,62)(H,63,64)(H,65,66)(H2,47,48,67);;1H2/q;+3;/p-3/t32-,33-;;/m0../s1/i;1-2;
Molecular Formula
C44H59GaN6O17
HBD / HBA
9 / 19
回転可能結合数
33
重原子数
68
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
よくある質問
This radioactive diagnostic agent is used in PET imaging to detect prostate cancer that has spread or recurred. It binds to prostate-specific membrane antigen (PSMA), a protein highly expressed on prostate cancer cells, allowing the imaging device to locate even small deposits of cancer. It is particularly useful when conventional imaging may not detect disease recurrence.
Functions as a diagnostic agent by providing contrast enhancement or radioactive tracer activity that enables visualization of anatomical structures or physiological processes during medical imaging.
Yes, Gallium Ga 68 Gozetotide is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL5095039. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 154572876. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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