Guanadrel Sulfate

CHEMBL3184143 Phase 4 承認済み Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
524.6 g/mol
LogP
Phase
4

A sulfate salt form of guanadrel, an antihypertensive agent that blocks the release of norepinephrine from sympathetic nerves to lower blood pressure. The sulfate salt provides a stable oral formulation for managing hypertension. Like other agents in this class, it can cause significant postural low blood pressure.

分子量

524.6000 g/mol

TPSA

249.00 Ų

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D構造

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SMILES

N=C(N)NCC1COC2(CCCCC2)O1.N=C(N)NCC1COC2(CCCCC2)O1.O=S(=O)(O)O

InChI

InChI=1S/2C10H19N3O2.H2O4S/c2*11-9(12)13-6-8-7-14-10(15-8)4-2-1-3-5-10;1-5(2,3)4/h2*8H,1-7H2,(H4,11,12,13);(H2,1,2,3,4)

Molecular Formula

C20H40N6O8S

HBD / HBA

6 / 10

回転可能結合数

4

重原子数

35

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

よくある質問

A sulfate salt form of guanadrel, an antihypertensive agent that blocks the release of norepinephrine from sympathetic nerves to lower blood pressure. The sulfate salt provides a stable oral formulation for managing hypertension. Like other agents in this class, it can cause significant postural low blood pressure.

Yes, Guanadrel Sulfate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3184143. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 68552. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

医学的免責事項

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.