Hydralazine Hydrochloride

CHEMBL542541 Phase 4 承認済み Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

196.6 g/mol

LogP

—

Phase

4

A hydrochloride salt form of hydralazine, a direct arteriolar vasodilator used to treat high blood pressure, heart failure, and hypertensive emergencies in pregnancy such as preeclampsia. The hydrochloride form is used in both oral tablets and injectable formulations for acute blood pressure lowering. Long-term use at high doses requires monitoring for drug-induced lupus-like syndrome.

分子量

196.6400 g/mol

TPSA

63.80 Å²

治療領域

Ovarian Cancer Cardiovascular Disease Non-Small Cell Lung Cancer Epilepsy Stroke Type 2 Diabetes Hypertension Breast Cancer Heart Failure Colorectal Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D構造

SVG PNG

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SMILES

Cl.NNc1nncc2ccccc12

InChI

InChI=1S/C8H8N4.ClH/c9-11-8-7-4-2-1-3-6(7)5-10-12-8;/h1-5H,9H2,(H,11,12);1H

Molecular Formula

C8H9ClN4

HBD / HBA

3 / 4

回転可能結合数

1

重原子数

13

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

よくある質問

A hydrochloride salt form of hydralazine, a direct arteriolar vasodilator used to treat high blood pressure, heart failure, and hypertensive emergencies in pregnancy such as preeclampsia. The hydrochloride form is used in both oral tablets and injectable formulations for acute blood pressure lowering. Long-term use at high doses requires monitoring for drug-induced lupus-like syndrome.

Yes, Hydralazine Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL542541. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 9351. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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構造

クイックデータ

分子式: C8H9ClN4
同義語: 3

外部リンク

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医学的免責事項

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.