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Ibalizumab

CHEMBL1743029 Phase 4 承認済み Antibody
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
— g/mol
LogP
—
Phase
4

This monoclonal antibody is used to treat HIV-1 infection in adults who are heavily treatment-experienced and whose infection is not adequately controlled with other antiretrovirals. It works by binding to CD4 receptors on T-cells in a way that blocks HIV entry into the cell without interfering with normal immune function. It is given by intravenous infusion every two weeks.

治療領域

Lymphoma HIV/AIDS Leukemia

作用機序

As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

機序

As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.

HBD / HBA

- / -

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

よくある質問

This monoclonal antibody is used to treat HIV-1 infection in adults who are heavily treatment-experienced and whose infection is not adequately controlled with other antiretrovirals. It works by binding to CD4 receptors on T-cells in a way that blocks HIV entry into the cell without interfering with normal immune function. It is given by intravenous infusion every two weeks.

As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.

Yes, Ibalizumab is an approved drug. It has reached clinical phase 4. It is classified as a Antibody.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1743029. Open-access bioactivity database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.

医学的免責事項

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.