Methysergide
Used for the prevention of severe, frequent migraines and cluster headaches that do not respond to other treatments. It works by blocking serotonin receptors involved in triggering migraine attacks, though it requires careful monitoring due to rare but serious side effects.
分子量
353.5000 g/mol
LogP
2.30
TPSA
57.50 Ų
リピンスキーの五則
適合
Pharmacokinetics (PK)
Pharmacodynamics (PD)
2D構造
Cite this structure
Embed this structure
SMILES
CC[C@@H](CO)NC(=O)[C@@H]1C=C2c3cccc4c3c(cn4C)C[C@H]2N(C)C1
InChI
InChI=1S/C21H27N3O2/c1-4-15(12-25)22-21(26)14-8-17-16-6-5-7-18-20(16)13(10-23(18)2)9-19(17)24(3)11-14/h5-8,10,14-15,19,25H,4,9,11-12H2,1-3H3,(H,22,26)/t14-,15+,19-/m1/s1
Molecular Formula
C21H27N3O2
HBD / HBA
2 / 3
回転可能結合数
4
重原子数
26
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
よくある質問
Used for the prevention of severe, frequent migraines and cluster headaches that do not respond to other treatments. It works by blocking serotonin receptors involved in triggering migraine attacks, though it requires careful monitoring due to rare but serious side effects.
Yes, Methysergide is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1065. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 9681. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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