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Mirikizumab

CHEMBL3990014 Phase 4 承認済み Antibody
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
— g/mol
LogP
—
Phase
4

This monoclonal antibody targets interleukin-23, a key signaling protein that drives chronic inflammation in conditions like ulcerative colitis and Crohn's disease, helping to reduce bowel inflammation and achieve remission. By selectively blocking the p19 subunit of IL-23, it quiets the specific inflammatory pathway most responsible for inflammatory bowel disease.

治療領域

Inflammatory Bowel Disease Psoriasis Obesity

作用機序

As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

機序

As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.

HBD / HBA

- / -

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

よくある質問

This monoclonal antibody targets interleukin-23, a key signaling protein that drives chronic inflammation in conditions like ulcerative colitis and Crohn's disease, helping to reduce bowel inflammation and achieve remission. By selectively blocking the p19 subunit of IL-23, it quiets the specific inflammatory pathway most responsible for inflammatory bowel disease.

As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.

Yes, Mirikizumab is an approved drug. It has reached clinical phase 4. It is classified as a Antibody.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3990014. Open-access bioactivity database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.

医学的免責事項

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.