Mitomycin
This chemotherapy drug acts like a prodrug that becomes activated inside cells to cross-link DNA strands, preventing cancer cells from dividing. It is used to treat bladder, breast, and other cancers, and can be applied directly into the bladder for bladder cancer treatment.
分子量
334.3300 g/mol
LogP
-0.40
TPSA
147.00 Ų
リピンスキーの五則
適合
治療領域
作用機序
Administered as an inactive precursor that is metabolically converted to its active form in the body. This prodrug design improves bioavailability, absorption, or targeted delivery compared to the active compound.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Administered as an inactive precursor that is metabolically converted to its active form in the body. This prodrug design improves bioavailability, absorption, or targeted delivery compared to the active compound.
2D構造
Cite this structure
Embed this structure
SMILES
CO[C@@]12[C@H](COC(N)=O)C3=C(C(=O)C(C)=C(N)C3=O)N1C[C@@H]1N[C@@H]12
InChI
InChI=1S/C15H18N4O5/c1-5-9(16)12(21)8-6(4-24-14(17)22)15(23-2)13-7(18-13)3-19(15)10(8)11(5)20/h6-7,13,18H,3-4,16H2,1-2H3,(H2,17,22)/t6-,7+,13+,15-/m1/s1
Molecular Formula
C15H18N4O5
HBD / HBA
3 / 8
回転可能結合数
4
重原子数
24
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
よくある質問
This chemotherapy drug acts like a prodrug that becomes activated inside cells to cross-link DNA strands, preventing cancer cells from dividing. It is used to treat bladder, breast, and other cancers, and can be applied directly into the bladder for bladder cancer treatment.
Administered as an inactive precursor that is metabolically converted to its active form in the body. This prodrug design improves bioavailability, absorption, or targeted delivery compared to the active compound.
Yes, Mitomycin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL105. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 5746. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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