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Moxetumomab Pasudotox

CHEMBL1743043 Phase 4 承認済み Antibody drug conjugate
Half-Life
—
Bioavailability
—
Protein Binding
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Molecular Weight
— g/mol
LogP
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Phase
4

An antibody–drug conjugate that combines an anti-CD22 antibody with a fragment of Pseudomonas exotoxin A, used to treat relapsed or refractory hairy cell leukemia. After binding to CD22 on malignant B cells, it is internalized and releases the toxin to kill the cancer cell.

治療領域

Lymphoma Leukemia

作用機序

As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

機序

As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.

HBD / HBA

- / -

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

よくある質問

An antibody–drug conjugate that combines an anti-CD22 antibody with a fragment of Pseudomonas exotoxin A, used to treat relapsed or refractory hairy cell leukemia. After binding to CD22 on malignant B cells, it is internalized and releases the toxin to kill the cancer cell.

As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.

Yes, Moxetumomab Pasudotox is an approved drug. It has reached clinical phase 4. It is classified as a Antibody drug conjugate.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1743043. Open-access bioactivity database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.

医学的免責事項

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.