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Nepafenac

CHEMBL1021 Phase 4 承認済み Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
254.3 g/mol
LogP
1.9
Phase
4

This non-steroidal anti-inflammatory eye drop is used to treat pain and inflammation after cataract surgery and to reduce the risk of swelling in the retina. It penetrates the eye tissues and converts to its active form to block inflammatory enzymes.

分子量

254.2800 g/mol

LogP

1.90

TPSA

86.20 Ų

リピンスキーの五則

適合

治療領域

Glaucoma Age-Related Macular Degeneration Pain Management Chronic Pain

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D構造

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
NC(=O)Cc1cccc(C(=O)c2ccccc2)c1N

                

                

                
                

                    
InChI

                    
InChI=1S/C15H14N2O2/c16-13(18)9-11-7-4-8-12(14(11)17)15(19)10-5-2-1-3-6-10/h1-8H,9,17H2,(H2,16,18)

                

                

                

                    
                    

                        
Molecular Formula

                        
C15H14N2O2

                    

                    
                    

                        
HBD / HBA

                        
2 / 3

                    

                    
                    

                        
回転可能結合数

                        
4

                    

                    
                    
                    

                        
重原子数

                        
19

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
よくある質問

                

                    
                    

                        
                        

                            
This non-steroidal anti-inflammatory eye drop is used to treat pain and inflammation after cataract surgery and to reduce the risk of swelling in the retina. It penetrates the eye tissues and converts to its active form to block inflammatory enzymes.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Nepafenac is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1021.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 151075.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
医学的免責事項

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.